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## Legacy: What Ötzi Has Meant for European Prehistory

Thirty years of research on Ötzi have made him one of the most studied individuals in the history of human archaeology. The sheer quantity of scientific output generated by his remains — hundreds of papers across fields from forensic medicine to archaeogenomics to paleoentomology to materials science — is unmatched for any prehistoric individual and rivals that of many historical figures.

What has this research meant for our understanding of European prehistory?

On the population genetics side, Ötzi’s genome has contributed to a picture of Copper Age Europe as a continent of regional diversity in ancestry composition, with different communities retaining different proportions of the three ancestry components that defined that period: ancient hunter-gatherer, Anatolian early farmer, and (shortly after Ötzi’s time) Eastern Steppe Herder. The Alpine isolation hypothesis — that the mountains preserved an unusually high early farmer ancestry in some communities — adds regional texture to what had seemed a relatively uniform Neolithic ancestry composition.

On the technology and material culture side, the analysis of Ötzi’s clothing, equipment, and food supplies has provided an unusually complete picture of Copper Age Alpine life. The sophistication of the clothing system, the complexity of the fire-starting kit, the evidence for long-range copper trade, and the multi-species diet all speak to a society with more technological capability, more long-range exchange, and more ecological knowledge than a simplistic view of “Stone Age” people might suggest.

On the medical and health side, Ötzi’s ancient genome and preserved tissues have contributed to research on the early history of multiple pathogens — H. pylori, Borrelia, Trichuris trichiura — and to understanding of the genetic disease risks carried by early European farmer populations. The 170-SNP skin pigmentation analysis developed for the 2023 study will be applicable to future ancient genomic research.

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